Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available in the supplementary material of this article. Supporting Information Filename Description smll71837-sup-0001-SuppMat.docx2.9 MB Supporting Information smll71837-sup-0002-DataFile.docx7.7 MB Supporting Information References 1, , , BMJ 2024, 384, 070856. 2, , , , , , Toxicon 2025, 258, 108335. 3, , , , , , , , , , , Nat. Rev. Dis.