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Yidie Ying

As seen in: AIChE Journal
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Articles

Establishment of bladder cancer spheroids and cultured in microfluidic platform for predicting drug response

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By Qiao Xiong, Ting Liu, Yidie Ying
| AIChE Journal Verified
Bladder cancer is a heterogeneous disease as distinct responses to first-line chemotherapy were observed, with a high resistance rate to chemotherapy. The establishment of tumor models for drug screening is essential. In this study, we cultured patient-derived tumor spheroids in microfluidic chips for drug sensitivity tests. It was proven that drug responses of spheroids closely resembled patients undergoing chemotherapy.
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Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA

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By Baiyun Wang, Shuxiong Zeng, Yidie Ying, Naidong Xing
| AACR Journal
Precision Medicine and Imaging Shuxiong Zeng, Yidie Ying, Naidong Xing, Baiyun Wang, Ziliang Qian, Zunlin Zhou, Zhensheng Zhang, Weidong Xu, Huiqing Wang, Lihe Dai, Li Gao, Tie Zhou, Jiatao Ji and Chuanliang Xu DOI: 10.1158/1078-0432.CCR-20-0401 Abstract Purpose: Urothelial carcinoma is a malignant cancer with frequent chromosomal aberrations. Here, we investigated the application of a cost-effective, low-coverage whole-genome sequencing technology in detecting all chromosomal aberrations.
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