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Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2
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Determinants of Zika virus host tropism uncovered by deep mutational scanning
Abstract Arboviruses cycle between, and replicate in, both invertebrate and vertebrate hosts, which for Zika virus (ZIKV) involves Aedes mosquitoes and primates1. The viral determinants required for replication in such obligate hosts are under strong purifying selection during natural virus evolution, making it challenging to resolve which determinants are optimal for viral fitness in each host.
Misperceived Risks of Zika-related Microcephaly in India
Nathan D. Grubaugh Nathan D. Grubaugh Correspondence Corresponding author. Affiliations Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA Search for articles by this author Farah Ishtiaq Yin Xiang Setoh Yin Xiang Setoh Affiliations Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia Search for articles by this author Albert I. Ko Albert I.
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