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Yinbo Niu on Muck Rack

Yinbo Niu

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Articles

Gut microbiota alteration contributes to bone marrow mesenchymal stem cells connexin43 response to high-fat diet induced obesity in mice

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By Kaiting Ning, Yufei Chen, Xuezhou Yang, Xiangya Dou, Dong-en Wang, Huiyun Xu, Shuaiting Liu, Yinbo Niu
| Nature Verified
Abstract Bone marrow mesenchymal stem cells (BMSCs) contribute to controlling adipose tissue homeostasis and may be a potential target for obesity therapy. Since lack of connexin43(Cx43) in mesenchymal stem cells (MSCs) is known to combat high-fat diet (HFD)-induced adiposity. Also, HFD is a well-known risk factor for gut microbiota dysbiosis. Here we attempt to address the interaction between HFD, gut microbiota, and Cx43 deficiency in BMSCs during the development of obesity.
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