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Xuezhou Yang

As seen in: Nature, Mary Ann Liebert, Inc.
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Articles

Gut microbiota alteration contributes to bone marrow mesenchymal stem cells connexin43 response to high-fat diet induced obesity in mice

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By Kaiting Ning, Yufei Chen, Xuezhou Yang, Xiangya Dou, Dong-en Wang, Huiyun Xu, Shuaiting Liu, Yinbo Niu
| Nature Verified
Abstract Bone marrow mesenchymal stem cells (BMSCs) contribute to controlling adipose tissue homeostasis and may be a potential target for obesity therapy. Since lack of connexin43(Cx43) in mesenchymal stem cells (MSCs) is known to combat high-fat diet (HFD)-induced adiposity. Also, HFD is a well-known risk factor for gut microbiota dysbiosis. Here we attempt to address the interaction between HFD, gut microbiota, and Cx43 deficiency in BMSCs during the development of obesity.
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Progress of Bone Marrow Mesenchymal Stem Cell Mitochondrial Transfer in Organ Injury Repair

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By Kaiting Ning, Xuezhou Yang, Dong-en Wang, Huiyun Xu
| Mary Ann Liebert, Inc.
Stem Cells and DevelopmentVol. 32, No. 13-14 Concise ReviewFree Access Abstract There has been an upsurge of interest in the bone marrow mesenchymal stem cell (BMSC) mitochondrial transfer as a potential therapeutic innovation in organ injury repair. Previous research mainly focused on its transfer routes and therapeutic effects. However, its intrinsic mechanism has not been well deciphered. The current research status needs to be summarized for the clarification of future research direction.
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