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Yinchao Tong

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Palmatine potentiates cefquinome efficacy against multidrug-resistant Escherichia coli via sulfur/taurine metabolism and oxidative stress modulation

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By Yining Zhang, Pengcheng Li, Hao Zhang, Honglin Xie, Saba Nasir, Wei Li, Juan Wang, Xinglong Wang, Weimin Zhang, Yinchao Tong, Leixin Zhu, Mingjin Fang, Suzhu Qing
| Frontiers
ORIGINAL RESEARCH article Volume 16 - 2025 | https://doi.org/10.3389/fmicb.2025.1644399 This article is part of the Research TopicPlant-derived Products for Developing New AntimicrobialsView all 12 articles Highlights • Broad synergy: All tested strains demonstrate the synergistic effects of palmatine and cefquinome. • Antibacterial mechanism: Palmatine disrupts membrane integrity, potentiates oxidative stress, and inhibits biofilm formation in E. coli.
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