Ying-Chu Lo

Supporting Information Filename Description nph70522-sup-0001-Supinfo.pdfPDF document, 33.3 MB Fig. S1 Sequence alignment. Fig. S2 Gene expressions in AhENA1 overexpressers and RNAi lines. Fig. S3 Nicotianamine secretion is not affected by knocking out At2g16980. Fig. S4 AtENA1 overexpressers have higher nicotianamine secretion and are more tolerant to excess zinc. Fig. S5 Zinc tolerance conferred by AhENA1 overexpression is reduced by excess iron. Fig.

1 INTRODUCTION The way in which populations adapt to their environment is a fundamental issue in biology. Domestication is widely used as a model for understanding adaptation as it corresponds to a recent adaptation process caused by strong, human-driven selection (Darwin, 1859, 1868). Humans have grown and bred various organisms, choosing individuals with the most interesting features for their particular uses or for consumption.