Ying-Erh Chou

Research Paper Volume 16, Issue 6 pp 5740—5750 1 Department of Pathology, Changhua Christian Hospital, Changhua, Taiwan 2 Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung, Taiwan 3 Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan 4 Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark 5 The Finsen Laboratory,...

Lung adenocarcinoma (LUAD) is the most frequent histological subtype of lung cancer, which is the most common malignant tumor and the main cause of cancer-related mortality globally. Recent reports revealed that long non-coding RNA (lncRNA) of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) plays a crucial role in tumorigenesis and metastasis development in lung cancer.

1 INTRODUCTION Oral tumorigenesis is a complex process, during which inherited factors are interconnected with numerous environmental risks in the predisposition to this disease.1 In addition to a plethora of genetic components that control DNA repair, cell proliferation and apoptosis,2 several acquired risks for oral cancer, including viral infection3 and habitual consumption of tobacco, alcohol and areca nuts,4-6 have been recognised.