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Ying-Han Wang on Muck Rack

Ying-Han Wang

As seen in: Nature, PLOS Biology, Cell Reports
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Articles

LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway - Oncogene

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By Jun Lu, Zhen-Hua Chen, Yong Huang, Ying-Han Wang, Zhi-Ping Liu, Liang-min Fu, Xiao-han Jin
| Nature Verified
Abstract LZTFL1 is a tumor suppressor located in chromosomal region 3p21.3 that is deleted frequently and early in various cancer types including the kidney cancer. However, its role in kidney tumorigenesis remains unknown.
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Synaptotagmin-7-mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants

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By Qiu-Wen Wang, Ying-Han Wang, Bing H. Wang, Yun Chen
| PLOS Biology Verified
Loading metrics Qiu-Wen Wang, Ying-Han Wang, Bing Wang, Yun Chen, Si-Yao Lu, Jun Yao Qiu-Wen Wang, Ying-Han Wang, Bing Wang, Yun Chen, Si-Yao Lu, Jun Yao Published: July 6, 2021 https://doi.org/10.1371/journal.pbio.3001323 ? This is an uncorrected proof. Figures Abstract Synaptotagmin-7 (Syt7) plays direct or redundant Ca2+ sensor roles in multiple forms of vesicle exocytosis in synapses.
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Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons

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By Yun Chen, Ying-Han Wang, Yi Zheng, Meijing Li
| Cell Reports Verified
Highlights • Syt1 corralled SVs within ∼12 nm to the AZ to initiate SV docking • PI(4,5)P2 functioned as the membrane partner of Syt1 to dock SVs • Syt1 and PI(4,5)P2 functioned prior to the SNARE complex formation Summary Synaptic vesicle (SV) docking is a dynamic multi-stage process that is required for efficient neurotransmitter release in response to nerve impulses.
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