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Ying-Ying Xu on Muck Rack

Ying-Ying Xu

As seen in: AIChE Journal, Wiley Online Library, Cell Press, EJSO - European Journal of Surgical Oncology
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Articles

Molecular switch‐mediated detection of EGFR deletion mutations and its application to cfDNA analysis

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By Ying-Ying Xu, Lu-Yan Wang, Protection Soochow Suzhou, Sheng-mei Zhou
| AIChE Journal Verified
In this study, we demonstrated that a molecular switch technology combined with blocker primers can detect the mutation of exon 19 in EGFR in real-time on a qPCR platform, and improve the detection sensitivity of low copy DNA samples. This advancement holds promise for enhancing early lung cancer diagnosis, promoting efficient non-invasive testing methods, and enabling personalized treatment strategies.
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The role of autophagy regulated by the PI3K/AKT/mTOR pathway and innate lymphoid cells in eosinophilic chronic sinusitis with nasal polyps

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By Chen Wang, Ying-Ying Xu, Jin-Jing Zhuo, Yi-Long Kai
| Wiley Online Library Verified
1 INTRODUCTION Chronic sinusitis with nasal polyps (CRSwNP) is a common disease that seriously affects the quality of life of patients. It is classified into two subtypes according to the infiltrating inflammatory cells: eosinophilic (eCRSwNP) and noeosinophilic subtypes.1 The etiology of eCRSwNP is complex and its pathogenesis is unclear. Staphylococcus aureus play an important role in the pathogenesis of eCRSwNP, not only by S.
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CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer

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By Ying-Ying Xu, Xing-Yu Zhong, Xiu-Ming Yuan, Miao Yin
| Cell Press Verified
(A) Arginine methylation of GAPDH is decreased by AdOx treatment. HEK293T cells overexpressing FLAG-tagged GAPDH were treated with increasing concentrations of the PRMT inhibitor AdOx for 24 hr as indicated. Arginine methylation of immunopurified GAPDH was detected with antibodies as indicated. Relative ratios of GAPDH methylation were calculated by normalizing against the GAPDH protein level. WCL, whole-cell lysate.
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