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Yingbi Zhou on Muck Rack

Yingbi Zhou

As seen in: Cell Press
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Articles

A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction

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By Jubayer Rahman, Jack A. Bibby, Parul Singh, Nicolas Merle, Erin West, Andrea C. Bohrer, Katrin D Mayer-Barber, Chengyu Liu, Lauren R. Brinster, Behdad Afzali, Ana Briones, Sara Alehashemi, Farzana Bhuyan, Jiahui Ge, Xijian Chen, Yingbi Zhou, Murray C.H. Clarke, Bin Liu, Raphaela Goldbach-Mansky, C. Henrique Serezani, Claudia Kemper
| Cell Press Verified
Keywords: Th1 cell responses complement complosome C5aR2 prostaglandin prostacyclin IL-1β Crohn’s disease rheumatoid arthritis cryopyrin-associated periodic fever syndrome CAPS Introduction Timely contraction of successful T helper 1 (Th1) cell responses, characterized by the downregulation of interferon (IFN)-γ production and co-expression of the anti-inflammatory cytokine interleukin-10 (IL-10), is essential in limiting Th1 cell-driven tissue pathologies1 and preventing autoimmune disease.2...
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