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Yingdeng Wang

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Hemoadsorption combined with hemodialysis versus hemodialysis alone on mortality in end-stage kidney disease: a randomized, open-label, multicenter trial

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By Wei Lu, Xi Zhang, Zhiyong Guo, Yueyi Deng, Zhaohui Ni, Rong Zhou, Niansong Wang, Chen Hong Yu, Xiaoqiang Ding, Qing Yu, Xiaonong Chen, Haidong Huang, Gang Ji, Yingdeng Wang, Gengru Jiang
| Nature Verified
Abstract The objective of this completed, randomized, open-label trial across 11 hemodialysis centers in Shanghai, China, was to evaluate whether hemoadsorption combined with hemodialysis (HAHD) reduces mortality compared to hemodialysis (HD) alone in end-stage kidney disease patients (maintenance HD ≥ 3 months, Kt/V ≥ 1.2). We randomized 1362 patients 1:1 to receive HAHD (n = 683) or HD alone (n = 679; mainly low-flux HD plus intermittent HDF). All 1362 randomized patients were analyzed.
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