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Yingfei Wang

As seen in: Nature, Wiley Online Library, MDPI, ACS Publications, Science Magazine, Royal Society of Chemistry, Cell Reports Medicine, Dove Medical Press, The Journal of Clinical Investigation
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Articles

Leukocyte-Hitchhiking Nanomedicine for Sensitized Ferroptosis Therapy Click to copy article link Article link copied!

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By Lingyu Zhong, Yingfei Wang, Fan Zhou
| dx.doi.org
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Leukocyte-Hitchhiking Nanomedicine for Sensitized Ferroptosis Therapy Click to copy article link Article link copied!

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By Lingyu Zhong, Yingfei Wang, Fan Zhou
| ACS Publications
Cite Jump to ExpandCollapse Biological and Medical Applications of Materials and InterfacesMarch 13, 2026 Leukocyte-Hitchhiking Nanomedicine for Sensitized Ferroptosis Therapy Click to copy article linkArticle link copied! Lingyu Zhong Lingyu Zhong State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China Yingfei Wang Yingfei Wang State Key Laboratory of Digital Medical Engineering, School of...
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HIF-activated priming of TRAIL-induced cell death determines epigenetic vulnerability in kidney cancer

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By Yong Wang, Yan Xiong, Shuiqiao Liu, Lei Bao, Xing Ping Qiu, Xiangyang Song, Vanina Toffessi Tcheuyap, Sipeng Wu, Mingyi Chen, James Brugarolas, Jian Jin, Yingfei Wang, Weibo Luo, Ilia Korboukh
| Cell Reports Medicine Verified
Keywords HIF VHL DNMT TRAIL death receptors epigenetic vulnerability cell death priming Introduction Clear cell renal cell carcinoma (ccRCC), comprising ∼80% of kidney cancer cases, is characterized by VHL (von Hippel-Lindau) tumor suppressor gene loss.1 VHL specifically recognizes prolyl-hydroxylated proteins including the transcription factor hypoxia-inducible factor (HIF) α subunits and acts as an E3 ubiquitin ligase mediating degradation of these substrates at the 26S proteasome.2,3,4 As...
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