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Yingfen Chen

As seen in: The Journal of Clinical Investigation
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Articles

Sinusoidal endothelial cells control liver inflammation and fibrosis

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By Yong He, Enjiang Lai, Yingfen Chen
| The Journal of Clinical Investigation
Abstract Liver fibrosis is a common pathological outcome of chronic liver disease and is driven by inflammatory responses. However, the early signals that initiate the inflammatory cascade remain poorly understood. Emerging evidence suggests that liver sinusoidal endothelial cells (LSECs) are not merely passive bystanders, but active regulators during liver fibrosis. In this issue of the JCI, Gan et al.
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