Yinghua Zhao
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An explainable biomedical foundation model via large-scale concept-enhanced vision–language pretraining
Abstract Artificial intelligence for medical imaging is required to be accurate and interpretable to clinicians. However, current multimodal biomedical foundation models often prioritize performance over explainability. Here we present ConceptCLIP, an explainable biomedical foundation model that achieves state-of-the-art diagnostic accuracy while delivering human-interpretable explanations across diverse imaging modalities.
Large-scale multi-sequence pretraining for generalizable MRI analysis in versatile clinical applications
Abstract Multi-sequence magnetic resonance imaging (MRI) is essential for clinical diagnosis because it enables comprehensive characterization of complex anatomy. However, its substantial heterogeneity limits the generalizability of deep learning models and hinders clinical translation.
A universal foundation model for grounded biomedical image interpretation
Abstract The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable. However, existing models generally lack the ability to simultaneously generate diagnostic findings and localize corresponding targets. This limitation makes it challenging to correlate AI-generated findings with visual evidence and interpret the results.
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