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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Circulating osteocalcin and incident dementia in the UK Biobank: a prospective cohort and exploratory multi-omics analysis
Abstract Background: We examined baseline relative circulating osteocalcin (OCN) in relation to incident dementia in UK Biobank. Methods: The longitudinal cohort comprised 43,942 participants; models used available complete records. Cox models used baseline OCN standardized per SD and follow-up censored at diagnosis, death, or November 27, 2024. Cognitive, MRI, and baseline molecular analyses were exploratory.
Dryland dominance in the slowdown of global vegetation carbon uptake
Abstract Rising atmospheric CO2 concentrations, temperature and vapour pressure deficit substantially influence plant photosynthesis and terrestrial carbon uptake, yet how these drivers interact to alter photosynthesis across different climate regimes remains unclear.
TaCNGC-2A suppresses seed dormancy and activates pre-harvest sprouting through modulating calcium and hormonal signaling pathways
Abstract Weak seed dormancy (SD) is prone to pre-harvest sprouting (PHS), which reduces cereal yield and quality. Here, through map-based analysis, we identify TaCNGC-2A, encoding a cyclic nucleotide-gated channel protein, as a negative regulator of wheat SD. Knocking out of TaCNGC-2A enhances SD and PHS resistance, with no yield penalty. Two transcription factors, TaMYB-5B and TaMYB-5D, directly bind to the T/A mutation site of TaCNGC-2A promoter to synergistically repress its expression.
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