Yingjun Zhao

Abstract Imbalanced accumulation of microtubule-associated protein tau containing three or four repeat domains (3 R or 4 R tau) is a core feature of tauopathies, which may result from alternative splicing of the MAPT mRNA. However, specific mechanisms yielding the imbalance were underinvestigated. Here, we identify a circular RNA (circTau6) derived from the MAPT gene in the human brain. CircTau6 was rolling-translated into novel 4 R tau variants, cTau4R.

Main text (Neuron 87, 963–975; September 2, 2015) We have become aware of errors in two figure panels (Figures 6B and 6E) in our paper. In the original Figure 6B, the NeuN image of the “Appoptosin + C3I” group was mispresented due to an unintentional copy-paste error. In Figure 6E, incorrect images for the NeuN and GFAP were used for the “Tau KO Control” group. These errors occurred during the assembly of the figure panels.

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.