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Yingluo Liu on Muck Rack

Yingluo Liu

As seen in: Science Magazine, Cell Press
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Articles

Bile acid synthesis impedes tumor-specific T cell responses during liver cancer

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By Siva Karthik Varanasi, Dan Chen, Yingluo Liu, Melissa Johnson, Cayla M. Miller, Kathryn Lande, Thomas Mann, Marcos G. Teneche, Eduardo Casillas, Kailash C. Mangalhara, Souradipta Ganguly, Michael A. LaPorta, Filipe Araujo Hoffmann, Varsha Mathew
| Science Magazine Verified
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A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies

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By Byers L.A, Zhiwei Liu, Yingluo Liu
| Cell Press Verified
Highlights • A proteomic and phosphoproteomic landscape of 43 KRAS mutant cancer cell lines • Multi-omic analysis reveals three subsets with distinct characteristics • Compensatory phosphoprotein biomarker analysis identifies new drug combinations • DOT1L and SHP2 inhibition synergistically treats a subset of KRAS mutant cancer Summary KRAS mutant cancer, characterized by the activation of a plethora of phosphorylation signaling pathways, remains a major challenge for cancer therapy.
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