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Dl-3-n-butylphthalide protects the heart against ischemic injury and H9c2 cardiomyoblasts against oxidative stress: involvement of mitochondrial function and biogenesis | Journal of Biomedical Science | Full Text
MI leads to the irreversible loss of cardiomyocytes, which has been reported as one of the leading causes of morbidity and mortality in China [22]. Therefore, it is particularly vital to explore new drugs for the treatment of MI. Our research provided the novel perspective that dl-3-n-butylphthalide (NBP), a neuroprotective drug used for the treatment of stroke in China, also exerted a cardioprotective effect via the improvement of mitochondrial function and biogenesis in MI.
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