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Clinical and morphological correlates of embryonic mosaicism: a retrospective cohort study of 10,469 blastocysts in PGT-A cycles
Abstract Background: Chromosomal mosaicism presents a significant clinical and diagnostic challenge in preimplantation genetic testing for aneuploidy (PGT-A) cycles. While the meiotic origins of uniform aneuploidy are well-established, the predictors and mechanisms driving mosaicism remain less understood. This study aimed to investigate the clinical and embryological factors associated with the occurrence of mosaic embryos.
Corifollitropin Alfa N02 versus Recombinant FSH for Ovarian Stimulation: A Phase 3 Trial and Safety Study in Chinese Women
ArticleArticles in Press105822Open access Affiliations & Notes 1Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University 2The Affiliated Hospital of Inner Mongolia Medical University 3Reproductive Medicine Center, The First Affiliated Hospital of Zhengzhou University 4Tongji Hospital Tongji Medical College of HUST 5The Third Affiliated Hospital of Guangzhou Medical University 6The First Affiliated Hospital of Anhui Medical University 7Chongqing Institute of Genetics...
Identification of metabolomic changes and potential therapeutic targets during ovarian aging
Introduction As an independent risk factor of female fertility, age has always been a top issue for discussion. The fecundability of women declines significantly after their mid −30 s [1], many scholars consider 35 years as the cut-off for reproductive age, and childbearing women over 35 years were defined as advanced maternal age (AMA) [1, 2].
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