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Molecular insights into assembly of the yeast CST-Polα/primase complex for telomere maintenance
Abstract Telomeric DNA replication involves coordinated action of telomerase and DNA polymerase α-primase (Polα/primase), which synthesize the G-strand and C-strand, respectively. The conserved Cdc13-Stn1-Ten1 (CST) complex critically regulates this process by both terminating telomerase activity and stimulating Polα/primase. While telomerase-mediated G-overhang synthesis is well studied, how CST-Polα/primase is recruited to telomeres for C-strand fill-in remains poorly understood.
Transformation of Bamboo: From Multiscale Fibers to Robust and Degradable Cellulose‐Based Materials for Plastic Substitution (Small 27/2025)
Juan Hu Research Institute of Wood Industry, Chinese Academy of Forestry, Haidian, Beijing, 100091 China Beijing Key Laboratory of Wood Science and Engineering, Beijing Forestry University, Haidian, Beijing, 100083 China Search for more papers by this author
Transformation of Bamboo: From Multiscale Fibers to Robust and Degradable Cellulose‐Based Materials for Plastic Substitution
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202411339-sup-0001-SuppMat.docx10.9 MB Supporting Information References 1, , , , , , , , Nature 2022, 603, 803. 2, , , , Nature 2021, 590, 423. 3, , , , , , , Nat. Sustain. 2023, 6, 599. 4, , , , , , , , , , Nature 2013, 494, 169. 5, , , , , Science 2020, 368, 1257. 6, , , , Science 2021, 373, 61. 7, , , , , Science 2021, 373, 51. 8, , , Nature 2016, 540, 354. 9, , , , , , , , , , Adv. Funct.
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