Yingqi Wang
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Multivariate approach of metal-chiral covalent organic frameworks for leaching-resistant asymmetric transfer hydrogenation
Abstract Achieving precise integration of chiral microenvironments and catalytic metals in covalent organic frameworks (COFs) remains a formidable challenge, often resulting in amorphous materials with poor stability and metal leaching. Here, we introduce a modular multivariate approach strategy coupled with post-synthetic metalation to engineer metal-chiral COFs (MCCOFs) with tunable crystallinity, porosity, and stereocontrol.
IgE drives osteoclastogenesis via binding with FcεRII in sparganosis-induced bone destruction
Abstract Progressive multi-vertebral osteolysis, frequently misdiagnosed as malignancy or tuberculosis, can also be driven by a previously unrecognized infectious trigger. Here we demonstrate that sparganosis induces pronounced IgE-dependent osteoclastogenesis and severe bone destruction. Single-cell RNA analysis of peripheral blood mononuclear cells identified the immune cell landscape of spinal sparganosis (SS) and the immunoglobulin-related pathways upregulated in naïve B cells derived from SS.
Pushed Out, Not Plugged In: Welfare Disjuncture in Hong Kong-Guangdong Cross-Border Ageing
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References 1990. “Disjuncture and Difference in the Global Cultural Economy.” Theory, Culture and Society 7, no. 2–3: 295–310. 2024.
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