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Multivariate approach of metal-chiral covalent organic frameworks for leaching-resistant asymmetric transfer hydrogenation
Abstract Achieving precise integration of chiral microenvironments and catalytic metals in covalent organic frameworks (COFs) remains a formidable challenge, often resulting in amorphous materials with poor stability and metal leaching. Here, we introduce a modular multivariate approach strategy coupled with post-synthetic metalation to engineer metal-chiral COFs (MCCOFs) with tunable crystallinity, porosity, and stereocontrol.
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