Yingrui Luo

1 INTRODUCTION Human papillomavirus (HPV) is a circular double-stranded DNA virus, approximately 8.0 kbp in size, that infects epithelial cells (keratinocytes). Over 200 HPV genotypes exist. Mostly, α-genotypes infect the mucosal epithelium, whereas the β-genotypes mainly infect the skin epithelium. Most HPV presents as a recessive infection or benign lesion, cleared by the immune system.

Backgrounds: Sarcoma (SARC) is a mesenchymal tumor which often responds poorly to systemic therapy. It is therefore important to look for possible biological markers that could tell the prognosis and the progression of SARC. Methods: A combined evaluation of the Cancer Genome Atlas (TCGA) and genotypic tissue expression (GTEx) portal was used to analyzeLMNB2 expression level in different types of cancer.

Research Paper Volume 17, Issue 1 pp 203—216 1 Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China 2 Guangdong Provincial Clinical Research Center for Laboratory Medicine, Guangzhou, Guangdong Province, China 3 GuangDong Second Province General Hospital, Neurosurgery Department (MH), Guangzhou, Guangdong Province, China 4 Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou,...