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Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis
1 Introduction Chronic kidney disease (CKD) is characterized by structural and functional impairment of the kidneys resulting from various causes and is characterized by a low glomerular filtration rate (GFR) and persistent kidney injury indicators for at least three months.[1] Kidney fibrosis, a common pathological feature of CKD and a precursor of end-stage renal failure, significantly threatens the quality of life of patients.[2] Fibrosis arises from repeated cycles of injury and repair,...
JoF | Free Full-Text | ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in Aspergillus niger
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Outer Membrane Porins Contribute to Antimicrobial Resistance in Gram-Negative Bacteria
1. Introduction The cell membranes of gram-negative bacteria are crucial for their survival and environmental adaptation. Generally, these membranes not only give gram-negative bacteria surface specificity but also operate as a functional and protective barrier for them []. Gram-negative bacteria have double membranes that include an outer membrane (OM) made up of outer membrane proteins (Omps) and other components [,].
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