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Yingxiu Chen

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Articles

Organoid modeling of lung branching morphogenesis and epithelial lineage specification

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By Mengjie Pan, Baomei Cai, Guanlie Li, Ruifang Zhang, Chuncao Deng, Huan Chen, Yingxiu Chen, Sihao Chen, Ziyu Feng, Xiongzhi Quan, Yunjing Du, Yiyi Cheng, Chunhua Zhou, Yudong Fu, Shujuan Liu, Dafeng Tao, Yangqing Tian, Jiajun Hou, Yongchang Huang, Yiwei Li, Shengyong Yu, Dajiang Qin, Duanqing Pei, Jiekai Chen, Man Zhang, Mingwei Min, Shangtao Cao
| Cell Press Verified
Keywords lung organoids branching morphogenesis proximal-distal patterning epithelial lineage specification regeneration Introduction Organoid technology provides a promising in vitro platform for modeling tissue development, regeneration, and disease by reconstructing organ-specific cell lineages in three dimensions.1 To date, although organoids have been established for multiple organs,1,2 including lung, intestine, liver, and brain, most epithelial organoids remain structurally simplistic.
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