Yingyi Chen

Abstract Background and aims: Inflammatory stimuli drive metabolic reprogramming in macrophages, supplying energy, reducing equivalents, and methyl donors required for the production of inflammatory mediators such as IL-1β; however, metabolic strategies to regulate this pathway remain unclear. Here, we aimed to define the mechanism by which D-mannose suppresses one-carbon metabolism in inflammatory macrophages and thereby epigenetically restrains inflammatory responses.

1 Introduction Small dams are abundant and widely distributed across mountainous regions. Hydropower, as a renewable energy source, has gained favour among many countries and investors, leading to rapid development (Dursun and Gokcol 2011; Nautiyal et al. 2011). However, its ecological consequences are well-documented.

Abstract Underwater visual perception of fish is a core technology in intelligent aquaculture systems. However, occlusion caused by overlapping fish remains a major obstacle to achieving accurate instance segmentation. Robust segmentation under such conditions requires large-scale datasets with both morphological diversity and pixel-level annotations.