Yingying Li
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Interfacial solvothermal synthesis of superhydrophilic ionic salt-derived chiral helical COFs with strong chiroptical activity
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Traditional chiral induction strategies for nonionic covalent organic frameworks (COFs) often produce disordered aggregates with low dissymmetry factors and weak chiroptical activity due to uncontrolled crystallization kinetics.
Molecular characteristics and pathogenicity-associated phenotypes of methicillin-resistant Staphylococcus aureus sequence type 398 clinical isolates from a women and children’s hospital in Southwest China
Abstract Background: Methicillin-resistant Staphylococcus aureus (MRSA) sequence type 398 (ST398), initially recognized as a livestock-associated lineage, has been increasingly reported in human infections. However, the molecular characteristics, antimicrobial resistance profiles, phylogenetic context, and pathogenicity-associated phenotypes of clinical MRSA ST398 isolates in China remain insufficiently defined.
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies
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Abstract Efficient priming of B cell precursors is a rate-limiting step in the induction of V2 apex broadly neutralizing antibodies (bNAbs)1,2. Here, we describe a novel germline-targeted HIV-1 Env (CAP256.OPT4) that increases the efficiency of V2 apex bNAb precursor priming by 30-400 fold compared with wild-type HIV-1 Envs and induces – in >90% of macaques – neutralization breadth that includes N130-containing viruses.
By Lorie Marchitto, Kshitij Wagh, Ryan Roark, Séverin Coléon, Hui Li, Ashwin N. Skelly, Michael P. Hogarty, Rumi Habib, Wenge Ding, Kasirajan Ayyanathan, Weimin Liu, Zizhang Sheng, Yicheng Guo, Lena Smith, Laura Sutherland, Younghoon Park, Andrew Connell, Frederic Bibollet-Ruche, Emily Lewis, Samantha Plante, Macy J. Akeley, Chengyan Zhao, John Carey, Christian Martella, Yingying Li, Mary S. Campion, Rebecca A. Osbaldeston, Colette G. Gordon, Amie Albertus, Justin Su, Chiaki Noguchi, Ying Tam, Christopher Barbosa, Xuduo Li, Agnes Walsh, Darrell J. Irvine, Raiees Andrabi, Robert Edwards, Edward F. Kreider, Drew Weissman, Lawrence Shapiro, Peter D. Kwong, Bette Korber, Barton F. Haynes, Kevin Saunders, Beatrice H. Hahn, George Shaw, Joena Bal, Jinery Lora, Melinda G. Lituchy, Khaled Amereh
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Nature
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