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Yingying Sang

As seen in: Nature, JAMA (The Journal of the American Medical Association), JAMA: Journal of the American Medical Association, Medscape, EClinicalMedicine, The Lancet, AHA/ASA Journals, Annals of Internal Medicine, Diabetes Care Magazine, Journal of the American Society of Nephrology (JASN) and
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Articles

Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals

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By Brendon L Neuen, Rupert W. Major, Morgan E. Grams, Yingying Sang, Josef Coresh, Shoshana H. Ballew, Aditya Surapaneni, Natalia Alencar de Pinho, Johan Ärnlöv, Clare Arnott, Samira Bell, Jarett Berry, Hermann Brenner, Elizabeth L Ciemins, Alexander Chang, Mary Cushman, James de Lemos, Juan Miguel Diaz-Tocados, Alfredo E. Farjat, Robert Fletcher, Ron T Gansevoort, Hiddo J. L. Heerspink, William G Herrington, Chuan Hong, Shih-Jen Hwang, Simerjot K Jassal, Philip A. Kalra, Ronit Katz, Sadiya Khan, Csaba P. Kovesdy, Florian Kronenberg, Jennifer Lees, Donald M. Lloyd-Jones, José Geraldo Mill, David Naimark, Chiadi E. Ndumele, Kevan R. Polkinghorne, Bruce M. Psaty, Patrick Schloemer, Michael G. Shlipak, Prabin Shrestha, Zean Song, Natalie Staplin, Dominik Steubl, Priya Vart, Frank L. J. Visseren, Mark Woodward, Kazumasa Yamagishi, Bessie A. Young, Charumathi Sabanayagam, José M. Valdivielso
| Nature Verified
Abstract The American Heart Association’s PREVENT equations estimate risk of total cardiovascular disease (CVD), atherosclerotic CVD (ASCVD), and heart failure (HF) to guide lipid and blood pressure-lowering therapy in people ages 30 to 79 years in the United States. The SCORE2 risk algorithm is used to estimate CVD risk for similar purposes in people ages 40 and older in Europe. Neither set of equations has been comprehensively validated in global observational cohorts and randomized trials.
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Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk: An Individual Patient–Level Meta-analysis: Annals of Internal Medicine: Vol 0, No 0

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By Morgan E. Grams, Yingying Sang
| Annals of Internal Medicine Verified
Get full access to this article View all available purchase options and get full access to this article. Supplemental Material References 1. Grams ME, Coresh J, Matsushita K, et al; Writing Group for the CKD Prognosis Consortium. Estimated glomerular filtration rate, albuminuria, and adverse outcomes: an individual-participant data meta-analysis. JAMA. 2023;330:1266-1277. [PMID: 37787795] doi: 10.1001/jama.2023.17002 2.
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"Development and Validation of the American Heart Association's PREVENT" by Sadiya S Khan, Kunihiro Matsushita et al.

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By Sadiya Khan, Kunihiro Matsushita, Yingying Sang, Shoshana H. Ballew
| Texas Medical Center
BACKGROUND: Multivariable equations are recommended by primary prevention guidelines to assess absolute risk of cardiovascular disease (CVD). However, current equations have several limitations. Therefore, we developed and validated the American Heart Association Predicting Risk of CVD EVENTs (PREVENT) equations among US adults 30 to 79 years of age without known CVD. METHODS: The derivation sample included individual-level participant data from 25 data sets (N=3 281 919) between 1992 and 2017.
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