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Yingying Shao on Muck Rack

Yingying Shao

As seen in: Color Research & Application, Nature, Wiley Online Library, PLOS ONE, Journal of Business Research, MDPI, Nutrition Journal, Canadian Journal of Infectious Diseases & Medical Microbiology, Emerald Publishing
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Articles

Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation

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By Jiang Wang, Hanlin L Wang, Chunpu Li, Shuni Wang, Guobin Liu, Yu An Zhang, Xiaobei Hu, Feng Gao, Gaoya Xu, Cong Li, Wei Zhu, Yunfei Ye, Yuqiang Shi, Yingying Shao, Yuxian Wang, Bo Wang, Yubo Zhou, He Huang, Jia Li, Hong liu, Runhua Du, Mingbo Su, Weijuan Kan, Jiangzhou Song
| Nature Verified
Abstract Epigenetic dysregulation is a fundamental cancer hallmark, and lysine demethylase 1 (LSD1) is a central target for cancer intervention. Developing novel LSD1 inhibitors with high selectivity, favorable bioavailability, and safety for acute myeloid leukemia (AML) remains challenging. We developed DC551040, a highly potent, selective irreversible LSD1 inhibitor with good tolerability in Phase I AML clinical trial (CTR20222026).
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IJMS | Free Full-Text | Genome-Wide Identification of Seven in Absentia E3 Ubiquitin Ligase Gene Family and Expression Profiles in Response to Different Hormones in Uncaria rhynchophylla

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By Jinxu Lan, Conglong Lian, Yingying Shao, Suiqing Chen
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Genome-Wide Mining of CULLIN E3 Ubiquitin Ligase Genes from Uncaria rhynchophylla

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By Yingying Shao, Detian Mu, Yu Zhou, Xinghui Liu
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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