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Yingying Yang MSc on Muck Rack

Yingying Yang MSc

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Articles

Physiologically Based Pharmacokinetic Modeling to Predict the Pharmacokinetics of Sacubitril/Valsartan in the Elderly with Renal or Hepatic Impairment Population

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By Ying Jin, Jiaqi Shao BSc, Yingying Yang MSc
| Wiley Online Library Verified
Introduction Sacubitril/valsartan is a fixed-dose combination drug acting as an angiotensin receptor-neprilysin inhibitor.1 It is primarily administered orally and widely used for treating heart failure and hypertension. The compound consists of sacubitril (a prodrug) and valsartan in a 1:1 molar ratio complexed as a sodium salt.
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