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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
An IRAK1-snRNA axis activates ATM to promote accurate repair within transcriptionally active chromatin
Keywords DNA damage response homologous recombination repair active transcription ATM snRNA IRAK1 MRE11-RAD50-NBS1 complex Get full text access Log in, subscribe or purchase for full access. References 1. Marnef, A. ∙ Cohen, S. ∙ Legube, G. Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care J. Mol. Biol. 2017; 429:1277-1288 2. García-Muse, T. ∙ Aguilera, A. Transcription-replication conflicts: how they occur and how they are resolved Nat. Rev. Mol. Cell Biol.
MSTO1 modulates RAD51 activity to safeguard mitochondrial DNA integrity and control immune responses
Abstract Pathogenic MSTO1 mutations cause cerebellar ataxia and congenital myopathy, yet their molecular mechanisms remain poorly understood. This study identifies MSTO1 as a crucial regulator of mitochondrial genome integrity through direct interaction with RAD51. MSTO1 deficiency enhances RAD51 binding to mitochondrial DNA (mtDNA), disrupting mtDNA replication and causing mtDNA damage.
Near-Infrared Fluorescent Probes Targeting LAG-3 for Guiding Immunomodulation and Efficacy Monitoring of Stereotactic Body Radiotherapy in Liver Cancer
Back to Journals » Journal of Hepatocellular Carcinoma » Volume 13 Authors Lu Q, Zeng P, An Y, Qin Y, Zhang J, Xu M, Wang C, Wu M, Chen R Received 30 December 2025 Accepted for publication 23 April 2026 Published 17 June 2026 Volume 2026:13 584426 DOI https://doi.org/10.2147/JHC.S584426 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
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