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Yingyu Qin

As seen in: Nature, Dove Medical Press
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Articles

MSTO1 modulates RAD51 activity to safeguard mitochondrial DNA integrity and control immune responses

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By Kaiqi Cheng, Zhanzhan Xu, Jiansong Liu, Yichen Pan, Chen Nie, Zuchao Mao, Haodong Lin, Yingyu Qin, Shuqi Cao, Xiaoman Li, Weibin Wang, Shiwei Li, Jiadong Wang
| Nature Verified
Abstract Pathogenic MSTO1 mutations cause cerebellar ataxia and congenital myopathy, yet their molecular mechanisms remain poorly understood. This study identifies MSTO1 as a crucial regulator of mitochondrial genome integrity through direct interaction with RAD51. MSTO1 deficiency enhances RAD51 binding to mitochondrial DNA (mtDNA), disrupting mtDNA replication and causing mtDNA damage.
Open in Who Shared Issue with article?

Near-Infrared Fluorescent Probes Targeting LAG-3 for Guiding Immunomodulation and Efficacy Monitoring of Stereotactic Body Radiotherapy in Liver Cancer

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By Qingyun Lu, Peng Zeng, Yingyu Qin
| Dove Medical Press
Back to Journals » Journal of Hepatocellular Carcinoma » Volume 13 Authors Lu Q, Zeng P, An Y, Qin Y, Zhang J, Xu M, Wang C, Wu M, Chen R Received 30 December 2025 Accepted for publication 23 April 2026 Published 17 June 2026 Volume 2026:13 584426 DOI https://doi.org/10.2147/JHC.S584426 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
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