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Yingyue Chai on Muck Rack

Yingyue Chai

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Articles

Functional human salivary gland organoids for tissue regeneration in chemically defined culture systems

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By Xinyuan Zhang, Jiaxuan Qiu, Xiaofeng Shan, Shang Xie, Yi Sui, Zhigang Cai, Yingyue Chai
| Cell Reports Medicine Verified
Results In a prior study, human submandibular gland (SMG) epithelial stem/progenitor cells were isolated and differentiated in vitro into primary salivary gland organoids using a keratinocyte medium with supplements (KM-S).16 To establish a robust 3D system for hSGOs, we compared KM-S with a chemically defined complete medium (CM) under two culture strategies (Matrigel-embedded vs. Matrigel-free) (Figure 1A).
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