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Zhigang Cai

As seen in: AIChE Journal, Wiley Online Library, BMJ Open, Frontiers in Immunology, MDPI, BMC Cancer, BioRxiv, Cell Reports, Cell Reports Medicine, Stem Cell Reports and
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Articles

Functional human salivary gland organoids for tissue regeneration in chemically defined culture systems

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By Xinyuan Zhang, Jiaxuan Qiu, Xiaofeng Shan, Shang Xie, Yi Sui, Zhigang Cai, Yingyue Chai
| Cell Reports Medicine Verified
Results In a prior study, human submandibular gland (SMG) epithelial stem/progenitor cells were isolated and differentiated in vitro into primary salivary gland organoids using a keratinocyte medium with supplements (KM-S).16 To establish a robust 3D system for hSGOs, we compared KM-S with a chemically defined complete medium (CM) under two culture strategies (Matrigel-embedded vs. Matrigel-free) (Figure 1A).
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Frontiers | Response to dabrafenib and trametinib combined with pembrolizumab in an elderly patient with lung adenocarcinoma of unknown primary harboring BRAF V600E mutation and high PD-L1 expression: a case report

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By Nan Li, Jing Hu, Zhigang Cai, Guangjin Bao
| Frontiers in Immunology
1 Introduction Lung adenocarcinoma is the most prevalent subtype of non-small cell lung cancer (NSCLC) and remains a main cause of cancer-related mortality worldwide (1). Molecular profiling and immunohistochemical analyses have dramatically transformed the therapeutic landscape of NSCLC, enabling the use of personalized therapies targeting specific oncogenic drivers (2).
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Piecewise Linear Approximation in Learned Index Structures: Theoretical and Empirical Analysis

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By Xianyu Zhu, Qiyu Liu, Guangyi Zhang, Zhigang Cai
| arXiv
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