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Yingyun Chen

As seen in: Cell Reports
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Articles

Endothelial FGF13 impairs angiogenesis by accelerating oxygen-independent HIF-1α degradation

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By Yingyun Chen, Zhouhao Tang, Meifan Jiang, Jiming Han, Zhicheng Hu Verified, Yiqiang Wu, Jiaqi Liang, Xiang Li, Mengyao Xiao, Wenya Liu, Chunhui Jiang, Xiaokun Li, Litai Jin, Weitao Cong, Zhaohang Wu, Yeyi Zheng
| Cell Reports Verified
Hindlimb ischemia model Hindlimb ischemia experiments were performed as described.45 Briefly, mice were anesthetized with 1.5%–2% isoflurane vaporized in oxygen and administered xylazine (6 mg/kg), and were placed on a 37°C heating pad to maintain body temperature. An 8 mm longitudinal incision was made in the left inguinal crease along the femoral vessels visible through the skin.
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Isolation, purification and anti-hypertensive effect of a novel Angiotensin I-Converting Enzyme (ACE) inhibitory peptide from Ruditapes philippinarum fermented with Bacillus natto

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By Xiang Gao, Qi Liu, Yuhong Jiang, Yingyun Chen
| Royal Society of Chemistry Verified
Hypertension is known as an important factor in cardiovascular diseases. Angiotensin-I-converting enzyme (ACE) inhibitor is one of the synthetic drugs that are widely used to control hypertension. Here, we have prepared and investigated the ACE inhibitory peptide from Ruditapes philippinarum fermented with Bacillus natto. The fermented product obtained under optimized fermentation conditions exhibited ACE inhibitory activity.
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