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Yingzhen Pei on Muck Rack

Yingzhen Pei

As seen in: Cell Reports, Stem Cell Reports
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Articles

Stem cell-based approach to identify regulatory TFs during mammalian cell differentiation

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By Yingzhen Pei, Siyi Li, Görkem Garipler, Kenji Kamimoto, Esteban O. Mazzoni
| Stem Cell Reports Verified
Keywords transcription factors development differentiation spinal cord motor neuron CRISPR screen scRNA-seq zinc finger Introduction Transcription factors (TFs) are crucial in embryo development and cell differentiation by binding DNA and regulating transcription. Understanding TF expression and activity is a key goal in developmental biology, as it can inform differentiation strategies for research and clinical use (Aydin and Mazzoni, 2019; Morris, 2016).
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