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Yinhua Jin on Muck Rack

Yinhua Jin

As seen in: Nature, Cell Press, eLife
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Articles

Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver

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By Abby Sarkar, Yinhua Jin, Brian DeFelice, Brian Defelice, Catriona Y. Logan
| eLife
Decision letter after peer review: Thank you for submitting your article "Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver" for consideration by eLife. Your article has been reviewed by 2 peer reviewers, including Pramod Mistry as Reviewing Editor and Reviewer #1, and the evaluation has been overseen by Mone Zaidi as the Senior Editor.
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EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation

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By Chenge Zhang, Yinhua Jin, Marco Marchetti, Mitchell R. Lewis
| Cell Press Verified
EGF signaling regulates the proliferation of intestinal stem cells in Drosophila. Development. 2011; 138: 1045-1055 Buchon N. Broderick N.A. Kuraishi T. Lemaitre B. DrosophilaEGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol. 2010; 8: 152 Jiang H. Grenley M.O. Bravo M.-J. Blumhagen R.Z. Edgar B.A. EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell. 2011; 8: 84-95 Xu N. Wang S.Q. Tan D. Gao Y.
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EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration

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By Peng Zhang, Jinyi Xiang, Jennifer Bandura, Yinhua Jin
| Nature Verified
The enteropathogen Pseudomonas entomophila (P.e.) secretes a virulence factor, haemolysin, that lyses ECs in the gut epithelium37. Previous studies reported that gut damage from P.e. upregulates EGFR ligands (Spi, Krn, Vn) and ligand-activating proteases (Rho1, 2, 4, 6) to activate the EGFR/MAP Kinase pathway in ISCs, promoting ISC growth and division10.
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