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Yining Li on Muck Rack

Yining Li

As seen in: Nature, Wiley Online Library, arXiv, MDPI, Royal Society of Chemistry, Cell Reports Physical Science, Dove Medical Press, The Journal of Biological Chemistry, Inkl
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Articles

A Bayesian Optimal Adaptive Clinical Trial Design for Sequentially Integrated Therapies

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By Yining Li, Jiaying Guo
| Wiley Online Library Verified
1 Introduction In clinical practice, treating complex syndromes often requires multiple therapeutic agents to address distinct clinical needs, delivered in a sequence dictated by the urgency and priority of the underlying conditions.
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Quantitative Proteomics Unveils Comprehensive Tissue-Specific VCP Interaction Networks in Mice

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By Nannan Wang, Yining Li, Chengzhi Wang, Huiming Zhu, Ziyue Zhou, Yibing Ding, Jingzi Zhang, Lei Fang, Bing Bai, Linru Shen
| Nature Verified
Abstract Valosin-containing protein (VCP), a conserved AAA ATPase hexamer, participates in multiple biological processes including ERAD, ubiquitin-dependent degradation by extracting misfolded proteins for proteasomal degradation. Although its interactions with cofactors are well-characterized, and its dysregulation is implicated in multisystem proteinopathy, amyotrophic lateral sclerosis, and cancer, the tissue-specific VCP interactomes underlying its functional versatility remain elusive.
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Diurnal Patterns of Accelerometer-Measured Physical Activity and Sleep in Relation to Cancer Risk: Findings From a Nationally Representative Study

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By Bowen Chen, Yue Wu, Yining Li
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Researchers can request the data used for the analysis from the NHANES (https://www.cdc.gov/nchs/nhanes/index.htm). All source code is publicly available on GitHub (https://github.com/garic019/IJC-25-3844). The original contributions presented in the study are included in the article/ further inquiries can be directed to the corresponding author.
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