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Yining Zhou

As seen in: Nature, arXiv, MDPI, Taylor & Francis Online, Journal of Sensors, No Film School, The Lantern
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Articles

Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia

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By Jiaquan Lin, Xiaoyan Shao, Tianshu Shi, Haosheng Wang, Pan Zhang, Yining Zhou, Na Liu, Yi He, Depeng Fang, Yong Shi, Yuze Ma, Bin Liu, Wang Gong, Wenshu Wu, Rui Peng, Chengzhi Wang, Tao Shen, Zhuoying Jiang, Yu Ben, Jianghui Qin, Zhihong Xu, Xiang Chen, Qing Jiang, Baosheng Guo
| Nature Verified
Abstract Exercise confers cognitive benefits in Alzheimer’s disease (AD), yet the underlying mechanisms remain incompletely understood. Skeletal muscle functions as an endocrine organ that secretes myokines which affect the homeostasis of extra-muscular organs, including the brain. Here we found that swimming exercise promotes secretion of skeletal muscle-derived extracellular vesicles (SKM-EVs), which are subsequently taken up via pinocytosis by microglia.
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A Unified Reinforcement Learning Framework for Dynamic User Profiling and Predictive Recommendation

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By Yining Zhou
| preprints.org
This version is not peer-reviewed. Submitted: 14 October 2025 You are already at the latest version This paper proposes a unified modeling approach based on reinforcement learning to address the problem of dynamic user profiling and behavior prediction.
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Self-Supervised Transfer Learning with Shared Encoders for Cross-Domain Cloud Optimization

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By Yining Zhou
| preprints.org
This version is not peer-reviewed. Submitted: 14 October 2025 You are already at the latest version This paper focuses on the optimization of cross-domain cloud computing tasks and proposes a unified modeling method that integrates transfer learning and self-supervised learning. The study first addresses the data distribution differences between the source and target domains by introducing a feature alignment mechanism.
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