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Yinmu Li

As seen in: Nature, Journal of Translational Medicine
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Articles

Akkermansia muciniphila -derived 5-MIAA blunts colitis-associated tumorigenesis by modulating colonic SLC26A3/pSTAT3 signaling

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By Binhai Shen, Hongbin Liu, Weifeng Huang, Ruo Xi Huang, Qian Zhou, Xinlong Lin, Mengyao Song, Zheng Chen, Yin Zhang, Yinmu Li, Yandong Guo, Lijun Zheng, Yangyang Liu, Fachao Zhi, Wendi Zhang
| Nature Verified
Abstract The interaction between gut microbiota and host genetic factors has been implicated in the development of colitis-associated colorectal cancer (CAC). Although Akkermansia muciniphila (Akk) has been studied in CAC, its role and molecular mechanism remain undetermined.
Open in Who Shared Issue with article?

Nicotinamide riboside attenuates radiation-induced intestinal injury by suppressing gasdermin E-mediated pyroptosis in intestinal epithelial cells - Journal of Translational Medicine

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By Qian Zhou, Le Liu, Xinlong Lin, Weifeng Huang, Yin Zhang, Yuyi Yang, Hongbin Liu, Wendi Zhang, Xinmei Zhao, Yangyang Liu, Gao Tan, Binhai Shen, Yinmu Li, Weiguang Qiao, Fachao Zhi
| Journal of Translational Medicine Verified
The construction of the IR model is based on previous methods [16]. The mice were irradiated at 1 Gy/min with 225kVp X-rays using a 0.3 mm copper filter in the irradiator (MultiRad, Faxitron, USA). The C57BL/6, the litter GsdmeΔIEC, and wild-type (WT) mice were gavaged with NR (400 mg/kg/day, MedChemExpress, Monmouth Junction, NJ, USA) or vehicle (equivalent volume of sterilized phosphate buffer per kg NR).
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