Yinuo Zhao

1 Introduction Antimicrobial resistance has gradually increased owing to the misuse and overuse of antibiotics [1]. The rise of super bugs has led to a pressing clinical challenge with a substantial disease burden, driving an urgent need for novel antimicrobial alternatives [2, 3]. Antimicrobial peptides (AMPs) have emerged as a promising class of therapeutics against multidrug-resistant (MDR) pathogens, offering mechanisms of action distinct from those of conventional antibiotics [4, 5].

ABSTRACT As a province with abundant cultural and tourism resources in the Yangtze River Delta, Anhui Province is currently facing the dilemma of transforming its tourism industry driving force structure. Studying how different driving factors affect the development of the tourism industry can better respond to internal and external environmental changes.

Keywords Piezo1 mechanosensitive ion channel physiological functions therapeutic target drug development Piezo1: an elusive channel but a promising therapeutic target Piezo1 is a crucial mechanosensitive ion channel protein. Piezo1 transduces physical mechanical forces into intracellular biological signals [1]. Piezo1 thereby plays a pivotal regulatory role in numerous physiological and pathological processes.