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Yinyin Chen

As seen in: Nature, Wiley Online Library, Frontiers, Frontiers in Immunology, MDPI, ACS Publications, Royal Society of Chemistry, Chemistry World, JACC (Journal of the American College of Cardiology), International Journal of Cardiology
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Articles

ZDHHC8-mediated S-palmitoylation of RAD21 causes mitochondrial dysfunction in diabetic nephropathy via inhibiting ACSM3 transcription

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By Yinyin Chen, Shaobin Duan, Yang Gao Verified, Weiying Zhang, Guoyong Liu, Jiayi Wang, Xiaofei Peng, Liyu He
| Nature Verified
Abstract Tubulointerstitial injury exerts a key role in diabetic nephropathy (DN) development; however, its potential mechanism is still unclear. We explored the role and molecular mechanisms of RAD21 cohesin complex component (RAD21) in mitochondrial dysfunction during tubulointerstitial injury of DN. We found that RAD21 was down-regulated, but its S-palmitoylation level was up-regulated in DN.
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Genetic burden across core genes of the PI3K–AKT–mTOR pathway is associated with susceptibility to microscopic polyangiitis: a Chinese cohort study

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By Lizhen Li, JING YANG, Chao Xue, Huan Zhong, Lijuan Tan, Xi Fang, Yinyin Chen, Liepeng Chu, Jinlan Rao, Shaoxia Shen
| Frontiers in Immunology
Abstract Background: The PI3K–AKT–mTOR signaling pathway plays a central role in immune regulation and has been implicated in autoimmune diseases. However, the contribution of genetic variation within key components of this pathway to microscopic polyangiitis (MPA) remains incompletely understood. Methods: We conducted a genetic association study in a Chinese cohort including MPA patients and controls.
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Direct Indazole Synthesis via Ruthenium(II)-Catalyzed Acceptorless Dehydrogenative Annulation of Alcohols and Arylhydrazines

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By Yinyin Chen, Hua Chen, Xueli Zheng, Weichao Xue
| dx.doi.org
Organic Letters Cite this: Org. Lett. 2026, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
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