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Yinyuan Ding

As seen in: The Journal of Biological Chemistry
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Articles

Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression

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By Allyson N. Hamlin, Sivaprakasam Chinnarasu, Yinyuan Ding, Xunde Xian
| The Journal of Biological Chemistry Verified
Reduced low-density lipoprotein receptor–related protein-1 (LRP1) expression in the liver is associated with poor prognosis of liver cirrhosis and hepatocellular carcinoma. Previous studies have shown that hepatic LRP1 deficiency exacerbates palmitate-induced steatosis and toxicity in vitro and also promotes high-fat diet–induced hepatic insulin resistance and hepatic steatosis in vivo.
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Low density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression

|
By Allyson N. Hamlin, Sivaprakasam Chinnarasu, Yinyuan Ding, Xunde Xian
| The Journal of Biological Chemistry Verified
Reduced low density lipoprotein receptor-related protein-1 (LRP1) expression in the liver is associated with poor prognosis of liver cirrhosis and hepatocellular carcinoma. Previous studies have shown that hepatic LRP1 deficiency exacerbates palmitate-induced steatosis and toxicity in vitro and also promotes high fat diet-induced hepatic insulin resistance and hepatic steatosis in vivo.
Open in Who Shared Issue with article?
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