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ATRX is a predictive marker for endocrinotherapy and chemotherapy resistance in HER2-/HR+ breast cancer through the regulation of the AR, GLI3 and GATA2 transcriptional network | Aging
Results The workflow of this study is shown in Figure 1A. To investigate the differentially expressed genes (DEGs) involved in the drug resistance of BC, we downloaded and merged three relevant GEO datasets to obtain a GSE1 dataset. Moreover, on eliminating the batch effect between different sequencing platforms, a total of 1,461 DEGs were screened, wherein 818 DEGs were downregulated and 650 DEGs were upregulated (Figure 1B, 1C).
ATRX is a predictive marker for endocrinotherapy and chemotherapy resistance in HER2-/HR+ breast cancer through the regulation of the AR, GLI3 and GATA2 transcriptional network | Aging
Research Paper Volume 15, Issue 24 pp 14996—15024 1 Cancer Research Center Nantong, Nantong Tumor Hospital, Affiliated Tumor Hospital of Nantong University, Nantong 226361, China 2 Department of Gynecology Oncology, Nantong Tumor Hospital, Affiliated Tumor Hospital of Nantong University, Nantong 226361, China 3 Department of Computer Science and Engineering, Tandon School of Engineering, New York University, Brooklyn, NY 11201, USA 4 Department of Surgery, Affiliated Tumor Hospital of Nantong...
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