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Yitong Yin

As seen in: Nature, Wiley Online Library, arXiv, MDPI, Biomed Central (BMC), BioRxiv, Cell Press, Cell Reports Medicine
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Articles

A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer

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By Yang Zheng, Caleb Cheng, Yizhi Cao, Gabriel Cruz, Yuping Zhang, Radha Paturu, Somnath Mahapatra, Jing Hu, Rahul Mannan, Hüseyin Karabürk, Rupam Bhattacharyya, Yitong Yin, Yi Zhao, Wenyan Liu, Xuhong Cao, Hui Xue, Chungen Li, Zhen J Wang, Stephanie Miner, Zachery R. Reichert, Rohit Mehra, Ulka Vaishampayan, Vaibhav Sahai, Lois S. Weisman, Ke Ding, Costas A. Lyssiotis, Yuzhuo Wang, Arul M. Chinnaiyan, Yuanyuan Qiao
| Cell Press Verified
Compounds ESK981 was provided by Esanik Therapeutics. Apilimod, Torin-1, bafilomycin A1, simvastatin, atorvastatin, WX8, MK-8245, ND-646, and Q-VD-OPh were purchased from Selleck Chemicals. PIK5-33d was provided by K. Ding. U18666A, YM-53601, and NB-598 were obtained from MedChemExpress. TVB-2640 was purchased from Nantong Hi-future Biotechnology. Doxycycline hydrochloride was obtained from Thermo Fisher Scientific. Thapsigargin was purchased from Cell Signaling Technology.
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Computer Science > Data Structures and Algorithms

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By Zhe Ju, Yitong Yin, Tianshun Miao
| arXiv
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
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Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors

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By Yizhi Cao, Caleb Cheng, Yitong Yin, Sarah Yee, Yang Zheng, Somnath Mahapatra, Fan Yang, Yi Zhao, Rupam Bhattacharyya, Stephanie Miner, Xuhong Cao, Rahul Mannan, Chungen Li, Vaibhav Sahai, Ke Ding, Costas A. Lyssiotis, Arul M. Chinnaiyan, Yuanyuan Qiao, Radha Paturu, Andrej Coleski, Shannon VanAken, Rüya Pakkan
| Cell Reports Medicine Verified
Keywords lysosome lipid metabolism mTOR ferritinophagy gastroenteropancreatic neuroendocrine tumor PIKfyve Introduction Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare malignancies arising from neuroendocrine cells in the gastrointestinal tract or pancreas and account for around 70% of all neuroendocrine tumors.1 Although uncommon, GEP-NET incidence has increased markedly over the past four decades.2 High-grade and metastatic GEP-NETs have poor prognosis, with 5-year survival...
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