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Yiying Chen on Muck Rack

Yiying Chen

As seen in: Nature, Wiley Online Library, British Pharmacological Society, MDPI, Taylor & Francis Online, Seeking Alpha, Science Magazine, Royal Society of Chemistry, Cell Press, Cell Reports Physical Science and
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Articles

STK39 promotes the evolution cascade of hepatocellular carcinoma by facilitating PKR/NF-κB-mediated macrophage inflammatory response

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By Chengfei Zhang, Xin McRae Chen, Hong Yao, Yiying Chen, Yong Zha, Ruoyu Shi, Bohao Chen, Yimeng Sang, Zhangjun Cheng, Fanggui Xu, Hongping Xia, Yangchun Zhou
| Nature Verified
Abstract ‘Liver injury-liver fibrosis/cirrhosis-liver cancer’ is the key evolution pathway of hepatocellular carcinoma (HCC), chronic inflammation serving as a major driving force in this process. However, the regulatory mechanisms underlying this process require further clarification. Here, the carcinogen-induced liver injury, liver fibrosis, and HCC models were investigated in the wild-type and STK39-knockout mice.
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The translation landscape of ovarian clear cell carcinoma indicates that RBM4 plays a pro-oncogenic role in tumor progression

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By Yiying Chen, Dongxu Lu, Jing He, Sumei Zhang, Xiaoxi Wang, Mei Li, Yuming Wang, Yike Gao, Anqi Wang, Kun Zhao, Zixin Zhang, Dan Guo, Shu Wang, Jian Sun, Yaqi Xing
| Nature Verified
Abstract Ovarian clear cell carcinoma (OCCC) is a highly aggressive gynecological malignancy characterized by distinct clinicopathological features and resistance to chemotherapy. Despite advances in multi-omics characterization, the translational regulatory landscape of OCCC remains unexplored. Here, we performed ribosome profiling to systematically investigate translation control mechanisms in OCCC.
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A National Biobank Framework for Rare Diseases: Standardized Infrastructure and Cross-Institutional Collaboration Accelerating Translational Innovation in China

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By Weida Liu, Ye Jin, Yaran Zhang, Anqi Wang, Yiying Chen, Fangyuan Li, Kun Zhao, Ruirui He, Dan Guo, Shuyang Zhang
| Cell Press Verified
PerspectiveOnline now100544Open access 1State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China 2Clinical Biobank, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China 3National Infrastructures for Translational Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science...
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