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Haplotype-resolved genome assembly sheds light on the evolutionary history of autohexaploid Tripidium arundinaceum
Abstract Tripidium arundinaceum, a wild perennial grass with exceptional stress tolerance, has been tested in sugarcane breeding. Its complex polyploid genome has hindered understanding of its evolution and adaptive traits. Here, we present a high-quality, haplotype-resolved reference genome for autohexaploid T. arundinaceum Hainan92-105 (2n = 6x = 60). T.
Recycling senescent cell lipids for targeted senotherapy
Abstract Senescent cells (SnCs) are increasingly recognized as key contributors to osteoarthritis, with conventional strategies centered on their elimination. However, senolytic approaches face mounting limitations, driving the need for refined interventions. Here, we exploit SnCs’ lipid metabolic signature to develop a senotherapeutic strategy.
Evolution of paleo‐duplicated chromosome pairs with enrichment of NBS‐LRR genes generated through ρ‐WGD in Poaceae
Data availability The sequencing data used in this study were obtained from public databases, including NCBI (https://www.ncbi.nlm.nih.gov/) and NGDC (https://ngdc.cncb.ac.cn/) and other similar repositories. Table lists the accession numbers for transcriptome data, while Table provides the accession numbers for epigenetic data. Some histone modification data were obtained from the high-throughput gene expression database (Gene Expression Omnibus, GEO) as bigwig files, with the accession no.
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