Yonghan Wu on Muck Rack

Yonghan Wu

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Articles

Bactericidal activity of mammalian histones is caused by large membrane pore formation

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By Summer J. Kasallis, Serena Abbondante, Paul J. Hurst, Michaela E. Marshall, Katherine McCarthy, Jean-Louis Bru, Kumar Perinbam, Eric Pearlman, Joseph Patterson, Steven Gross, Albert Siryaporn, Leora Duong, Yonghan Wu
| Cell Reports Verified
Keywords antimicrobial synergy antimicrobial peptides innate immunity bacterial membrane pores colistin polymyxin histones pore formation lipopolysaccharide antibiotics Research topic(s) CP: Microbiology Introduction Histones are eukaryotic proteins that were originally reported as antimicrobial agents over 80 years ago1 but more recently have been studied mostly for their role in condensing chromosomal DNA and regulating transcription.
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