Yoshiki Wada on Muck Rack

Yoshiki Wada

As seen in: Physical Review B
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Articles

Therapeutic ability of extracellular vesicles derived from angio-miRNA-modified mesenchymal stromal cells in ischemic animal models

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By Yoshiki Wada, Toshifumi Kudo, Ayako Inoue, Tomomi Kusakabe
| biorxiv.org
Abstract Background: Regenerative therapy using extracellular vesicles (EVs) is expected to be an option for supportive therapy of chronic limb-threatening ischemia. In this study, we examined the angiogenic potential of EVs derived from genetically modified MSCs, focusing on the angio-miRNAs in these vesicles. Methods: Bone marrow mesenchymal stromal cells (BM-MSCs) were transfected with a lentiviral vector containing specific angio-miRNAs (miRNA-126, -135b, or -210).
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MicroRNAs in BM-MSC-Derived Extracellular Vesicles Promote Angiogenesis: An In Vitro Model Supporting Clinical Application in Critical Limb Ischemia

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By Tomomi Kusakabe, Yoshiki Wada, Tomohiro Umezu, Masahiko Kuroda
| preprints.org
1. Introduction Critical limb ischemia (CLI), a severe manifestation of peripheral arterial disease, continues to present a major clinical challenge due to the scarcity of effective treatment options for patients who are not candidates for surgical or endovascular revascularization.
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Fermi-edge singularity and related emission from degenerate semiconductors: Transition from a spontaneous to a stimulated process

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By Toshihiro Nakamura, Aika Tashiro, Yutaka Adachi, Yoshiki Wada
| Physical Review B
We report on the observation of Fermi-edge singularity in the optical absorption and emission spectra of high-quality degenerate Ga-doped ZnO (GZO) films from cryogenic to room temperature, as well as on the related stimulated emission under femtosecond laser pulse excitation.
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