YOU WEI CHEN

Abstract Divergent transcription is a critical marker of active transcriptional regulatory elements (TREs), including enhancers and promoters, in mammals. However, distal elements with unidirectional transcriptional patterns are often overlooked, leaving their identity and function poorly understood. Here, we perform a systematic comparison between divergent and unidirectional elements, revealing their distinct architectural and functional features.

1 Introduction Enhanced recovery after surgery (ERAS) is a multimodal multidisciplinary approach that can enhance recovery and reduce complications by using several care improvement processes.[1] Among them, peripheral nerve block is critical for ERAS since it is a widely used clinical procedure that performs precise pain control and decreases nausea, vomiting, and the likelihood of respiratory depression due to the reduction of opioid consumption.[2] Currently, local anesthesia is an...